Challenge Studies
Studies to prove the efficacy of Nobilis Salenvac T against S. enteritidis and S. typhimurium infections in poultry.
Effect on shedding
Shedding of wild type Salmonella Typhimurium from the gastrointestinal tract of broiler breeders vaccinated with Nobilis Salenvac T and non vaccinated control birds was evaluated after exposure to seeder birds (birds known to be excreting high levels of Salmonella Typhimurium).
Shedding of Salmonella Typhimurium was evaluated by cloacal swabs sampling.
The graphs below show the percentage of positive isolation from the cloacal swabs and the percentage of birds, which were low, medium or high shedders.
Conclusion
- Nobilis Salenvac T reduces the shedding of Salmonella Typhimurium.
- Nobilis Salenvac T shows a reduction of low, medium and high shedders in the vaccinated birds.
Further results of this trial also indicate:
Reduction of egg transmission of S. typhimurium
Method
- Broiler breeders vaccinated with Nobilis Salenvac T were challenged intravenously with S. Typhimurium at 20 weeks of age.
- Eggs were tested for S. Typhimurium
Results
Conclusion
Nobilis Salenvac T reduces the vertical transmission of S. Typhimurium via the egg
Reduced shedding of S. typhimurium in broilers
Method
- Shedding of S. Typhimurium from broilers from vaccinated and unvaccinated breeders was compared.
- The birds were challenged at day old through contact with "seeder" birds.
Results
Conclusion
Vaccination of broiler breeders with Nobilis Salenvac T leads to a reduction in shedding of S. Typhimurium.