Nobilis Salenvac T additional trials and studies

Additional trials and studies have been carried out on the effects when birds are vaccinated with Nobilis Salenvac T. Below an overview of the additional trails and studies

Cross Protection Studies

Efficacy of Nobilis Salenvac T against S. Heidelberg and S. Agona*

*International dossier

Salmonella Typhimurium , S. Heidelberg and S. Agona belong to Group B in the Kaufmann-White classification scheme for Salmonella.

S. Heidelberg study

Method

  • Nobilis Salenvac T vaccinated birds and a control group of unvaccinated chickens were challenged with S. Heidelberg.
  • Salmonella shedding through faeces was monitored for 21 days.

* International dossier Nobilis Salenvac T

Results

The graph below compares shedding of S. Heidelberg from vaccinated and unvaccinated chickens.

shedding of  S Heidelberg in vaccinated and unvaccinated chickens

Conclusion

Nobilis Salenvac T reduces shedding of Salmonella Heidelberg

S. Agona study

Method

  • Nobilis Salenvac T vaccinated birds and a control group of unvaccinated chickens were challenged with S. Agona.
  • Salmonella shedding through faeces was monitored for 21 days.

Results

The graph below compares shedding of S. Agona from vaccinated and unvaccinated birds.

% shedding of  S Agona in vaccinated and unvaccinated chickens

Conclusion

Nobilis Salenvac T reduces shedding of Salmonella Agona.

Antibodies in the eggs of vaccinated hens

Vaccination of laying hens with a live Salmonella vaccine or with an inactivated vaccine showed that growth of Salmonella Enteritidis was significantly reduced in these eggs compared to eggs from unvaccinated hens and hens vaccinated with a live S. Enteritidis vaccine.

For full details of the study see the poster presented at the 13S International Symposium Salmonella and Salmonellosis, 10-12 May 2006, St Malo, France.

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