Nobilis Salenvac T additional trials and studies
Additional trials and studies have been carried out on the effects when birds are vaccinated with Nobilis Salenvac T. Below an overview of the additional trails and studies
- Cross protection against other group B Salmonella serotypes
- Antibodies in eggs from birds vaccinated with Nobilis Salenvac-T
- Reduction of egg transmission of S. Typhimurium
- Reduced shedding of S. Typhimurium in broilers
Cross Protection Studies
Efficacy of Nobilis Salenvac T against S. Heidelberg and S. Agona*
*International dossier
Salmonella Typhimurium , S. Heidelberg and S. Agona belong to Group B in the Kaufmann-White classification scheme for Salmonella.
S. Heidelberg study
Method
- Nobilis Salenvac T vaccinated birds and a control group of unvaccinated chickens were challenged with S. Heidelberg.
- Salmonella shedding through faeces was monitored for 21 days.
* International dossier Nobilis Salenvac T
Results
The graph below compares shedding of S. Heidelberg from vaccinated and unvaccinated chickens.

Conclusion
Nobilis Salenvac T reduces shedding of Salmonella Heidelberg
S. Agona study
Method
- Nobilis Salenvac T vaccinated birds and a control group of unvaccinated chickens were challenged with S. Agona.
- Salmonella shedding through faeces was monitored
for 21 days.
Results
The graph below compares shedding of S. Agona from vaccinated and unvaccinated birds.

Conclusion
Nobilis Salenvac T reduces shedding of Salmonella Agona.
Antibodies in the eggs of vaccinated hens
Vaccination of laying hens with a live Salmonella vaccine or with an inactivated vaccine showed that growth of Salmonella Enteritidis was significantly reduced in these eggs compared to eggs from unvaccinated hens and hens vaccinated with a live S. Enteritidis vaccine.
For full details of the study see the poster presented at the 13S International Symposium Salmonella and Salmonellosis, 10-12 May 2006, St Malo, France.
